IFNgammafunction

由 D Jorgovanovic 著作 · 2020 · 被引用 600 次 — IFN-γ acts as a cytotoxic cytokine together with granzyme B and perforin to initiate apoptosis in tumor cells [9, 10], but also enables the ...

IFN-γ, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral, some bacterial and protozoan infections. IFN-γ is ...

由 K Schroder 著作 · 2004 · 被引用 5435 次 — IFN-γ is a remarkable cytokine that orchestrates many distinct cellular programs through transcriptional control over large numbers of genes.

由 K Schroder 著作 · 2004 · 被引用 5443 次 — Interferon-gamma (IFN-gamma) coordinates a diverse array of cellular programs through transcriptional regulation of immunologically relevant genes.

由 F Castro 著作 · 2018 · 被引用 1041 次 — Specifically, IFN-γ plays a major role in activating anticancer immunity, by promoting the activity of CD4 T helper type 1 cells, CD8 cytotoxic ...

由 P Bhat 著作 · 2017 · 被引用 418 次 — Interferon gamma (IFNγ) is a key moderator of cell-mediated immunity with diverse, mainly pro-inflammatory actions on immunocytes and target ...

由 G Tau 著作 · 1999 · 被引用 317 次 — Overview. Interferon‐gamma (IFN‐γ) is a cytokine that plays an important role in inducing and modulating an array of immune responses.

由 H Ding 著作 · 2022 · 被引用 21 次 — Its principal functions are to recognize non-self antigens, generate responses to eliminate the pathogens or pathogen-infected cells maximally, and then ...

Interferon gamma is produced by T lymphocytes when stimulated with antigens or mitogens. Interferon gamma binds to a distinct receptor, the interferon gamma ...